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KMID : 1035420200080010159
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Journal of The Korean Society of Integrative Medicine
2020 Volume.8 No. 1 p.159 ~ p.168
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The Effects of 12 Weeks Combined Exercise on Brain Nerve Growth Factor, Inflammation-Related factor
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Seo Jeong-Pyo
Heo Jun-Hoe
Kim Hyun-Jun
Park Jang-Jun
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Abstract
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Purpose: To provide data on exercise prescription for obesity management and prevention of cardiovascular disease in girl’s high school and to prepare basic data for more effective exercise program for lifestyle improvement and prevention of lifestyle-related diseases. This study examines the effects on the factors and inflammatory factors, and the relationship between obesity factor and brain neuron cell production factor and inflammatory factor changes by complex exercise.
Methods: The subjects of the study were obese students with a body fat percentage of 30% or higher after obtaining body fat percentage of high school girls in C-city. Among them, 20 patients who wanted to participate in the program of this study and did not participate in special exercise and diet therapy within the last 6 months were radio-sampled into 10 groups of exercise group and control group, but attendance rate was low and The final exercise group (9) and control group (9) were measured, except for one student who did not respond.
Results: Analysis of the range of variation in body composition, BMI, lean body mass, and the interaction between the groups showed significant differences (p<.05). TC, TG, HDL-C, and LDL-C as variables of blood lipids, TC and TG were not significantly different and TG was significantly different (p<.05). HDL-C showed a significant difference (p<.01) in interactions, an increase in exercise group, and a significant decrease in control group (p<.05). There was a significant difference (p<.05) in BDNF interaction, an increase in the exercise group and a decrease in the control group, but no significant difference. NGF tended to increase in both exercise and control groups. IL-6 had a significant difference in timing (p<.05) and significantly decreased (p<.01) in the exercise group, and TNF-α interacted with timing (p<.05) ), and a significant increase in the control group.
Conclusion: This study confirmed 12-week compound exercise program was effective in increasing the expression of basal fitness or CNS factor, but not enough to actually improve brain function. Fat mass and obesity are also affecting vascular inflammatory factors.
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KEYWORD
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brain-deriver neurotrophic factor, combined exercise, interukin-6, nerve growth factor, tumor necrosis factor-α
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